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Bayesian adaptive model selection for optimizing group sequential clinical trials

This article presents a new approach to the problem of deriving an optimal design for a randomized group sequential clinical trial based on right-censored event times. We are motivated by the fact that, if the proportional hazards assumption is not met, then a conventional design’s actual power can...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Stat Med
Päätekijät: Wathen, J. Kyle, Thall, Peter F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587123/
https://ncbi.nlm.nih.gov/pubmed/18752257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3381
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