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Bayesian adaptive model selection for optimizing group sequential clinical trials
This article presents a new approach to the problem of deriving an optimal design for a randomized group sequential clinical trial based on right-censored event times. We are motivated by the fact that, if the proportional hazards assumption is not met, then a conventional design’s actual power can...
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| Publicado no: | Stat Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587123/ https://ncbi.nlm.nih.gov/pubmed/18752257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3381 |
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