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A Simulation Study of Outcome Adaptive Randomization in Multi-arm Clinical Trials

BACKGROUND: Randomizing patients among treatments with equal probabilities in clinical trials is the established method to obtain unbiased comparisons. In recent years, motivated by ethical considerations, many authors have proposed outcome adaptive randomization, wherein the randomization probabili...

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Detalhes bibliográficos
Publicado no:Clin Trials
Main Authors: Wathen, J. Kyle, Thall, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634533/
https://ncbi.nlm.nih.gov/pubmed/28982263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774517692302
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