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A Teaching Experiment to Elucidate a Cation-π Effect in an Alkyne Cycloaddition Reaction and Illustrate Hypothesis Driven Design of Experiments

An organic chemistry experiment is described that is based on recent research to elucidate a novel cation-π interaction between tetraalkammonium cations and propargyl hydrazines. This non-bonded interaction is a key component of the mechanism of ammonium-catalyzed intramolecular cycloaddition of nit...

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Detalhes bibliográficos
Publicado no:J Chem Educ
Main Authors: St.Germain, Elijah J., Horowitz, Andrew S., Rucco, Dominic, Rezler, Evonne M., Lepore, Salvatore D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708165/
https://ncbi.nlm.nih.gov/pubmed/29200498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jchemed.6b00318
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