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The Non-Homologous End Joining Protein PAXX Acts to Restrict HSV-1 Infection

Herpes simplex virus 1 (HSV-1) has extensive interactions with the host DNA damage response (DDR) machinery that can be either detrimental or beneficial to the virus. Proteins in the homologous recombination pathway are known to be required for efficient replication of the viral genome, while differ...

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Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Trigg, Ben J., Lauer, Katharina B., Fernandes dos Santos, Paula, Coleman, Heather, Balmus, Gabriel, Mansur, Daniel S., Ferguson, Brian J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707549/
https://ncbi.nlm.nih.gov/pubmed/29144403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9110342
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