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Restricting the ligation step of non-homologous end-joining

Non-homologous end-joining is an important pathway for repairing DNA double-strand breaks. The budding yeast Saccharomyces cerevisiae possesses two proteins, Nej1/Lif2 and Ntr1/Spp382, which play a role in restricting the activity of Dnl4-Lif1, the complex that executes the final ligation step of th...

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Autores principales: Chovanec, Miroslav, Wilson, Thomas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139902/
https://ncbi.nlm.nih.gov/pubmed/17977804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.09.007
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