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Restricting the ligation step of non-homologous end-joining
Non-homologous end-joining is an important pathway for repairing DNA double-strand breaks. The budding yeast Saccharomyces cerevisiae possesses two proteins, Nej1/Lif2 and Ntr1/Spp382, which play a role in restricting the activity of Dnl4-Lif1, the complex that executes the final ligation step of th...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2139902/ https://ncbi.nlm.nih.gov/pubmed/17977804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.09.007 |
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