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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection
Early after infection, the retroviral RNA genome is reverse transcribed to generate a linear cDNA copy, then that copy is integrated into a chromosome of the host cell. We report that unintegrated viral cDNA is a substrate for the host cell non-homologous DNA end joining (NHEJ) pathway, which normal...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150207/ https://ncbi.nlm.nih.gov/pubmed/11406603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3272 |
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