Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

Early after infection, the retroviral RNA genome is reverse transcribed to generate a linear cDNA copy, then that copy is integrated into a chromosome of the host cell. We report that unintegrated viral cDNA is a substrate for the host cell non-homologous DNA end joining (NHEJ) pathway, which normal...

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Bibliografiske detaljer
Main Authors: Li, Ling, Olvera, Jennifer M., Yoder, Kristine E., Mitchell, Richard S., Butler, Scott L., Lieber, Michael, Martin, Sandra L., Bushman, Frederic D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150207/
https://ncbi.nlm.nih.gov/pubmed/11406603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3272
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