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A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin
Cellular proliferation is antagonistically regulated by canonical and noncanonical Wnt signals; their dysbalance triggers cancers. We previously showed that a multimodular signal transducer, Daple, enhances PI3-K→Akt signals within the noncanonical Wnt signaling pathway and antagonistically inhibits...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706997/ https://ncbi.nlm.nih.gov/pubmed/29021338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0405 |
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