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Matrix metalloproteinase MMP9 maintains epithelial barrier function and preserves mucosal lining in colitis associated cancer

In colitis associated cancer (CAC), chronic inflammation exposes the epithelial mucosal defensive lining to inflammatory mediators such as cytokines and anti-microbial peptides (AMPs) causing the dysbiosis of microbiota population and the dysregulation of immune response. Matrix Metalloproteinases (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pujada, Adani, Walter, Lewins, Patel, Aashka, Bui, Tien Anh, Zhang, Zhan, Zhang, Yuchen, Denning, Timothy Luke, Garg, Pallavi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706902/
https://ncbi.nlm.nih.gov/pubmed/29212256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21841
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