Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

Matrix metalloproteinases (MMP) play an important role in pathogenesis of inflammatory bowel disease (IBD). Two known gelatinases, MMP-2 and MMP-9, are upregulated during IBD. Epithelial-derived MMP-9 is an important mediator of tissue injury in colitis, whereas MMP-2 protects against tissue damage...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Garg, Pallavi, Vijay-Kumar, Matam, Wang, Lixin, Gewirtz, Andrew T., Merlin, Didier, Sitaraman, Shanthi V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2009
Ämnen:
Inflammation/Immunity/Mediators
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643910/
https://ncbi.nlm.nih.gov/pubmed/19171847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90454.2008
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk