Notch1 Regulates the Effects of Matrix Metalloproteinase-9 on Colitis-Associated Cancer in Mice

BACKGROUND & AIMS: Inflammatory bowel disease increases the risks for colon cancer and colitis-associated cancer (CAC). Epithelial cell-derived matrix metalloproteinase (MMP)9 mediates inflammation during acute colitis and the cleavage and activation of the transcription factor Notch1, which pre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Garg, Pallavi, Jeppsson, Sabrina, Dalmasso, Guillaume, Ghaleb, Amr M., McConnell, Beth B., Yang, Vincent W., Gewirtz, Andrew T., Merlin, Didier, Sitaraman, Shanthi V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186860/
https://ncbi.nlm.nih.gov/pubmed/21723221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.056
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge