Expression of PTEN‐long mediated by CRISPR/Cas9 can repress U87 cell proliferation

PTEN is a tumour suppressor that is frequently mutated in a variety of cancers. Hence, PTEN has significant potential as a therapeutic molecule. PTEN‐long is an alternative translation variant, with an additional 173 amino acids added to the N‐terminal of the canonical PTEN when CUG of the mRNA is u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Mol Med
Egile Nagusiak: Fang, Na, Gu, Tingxuan, Wang, Yahui, Wang, Shuzhen, Wang, Fengling, An, Yang, Wei, Wenqiang, Zhang, Weijuan, Guo, Xiangqian, Nazarali, Adil J, Ji, Shaoping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706501/
https://ncbi.nlm.nih.gov/pubmed/28631420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13236
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