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Expression of PTEN‐long mediated by CRISPR/Cas9 can repress U87 cell proliferation
PTEN is a tumour suppressor that is frequently mutated in a variety of cancers. Hence, PTEN has significant potential as a therapeutic molecule. PTEN‐long is an alternative translation variant, with an additional 173 amino acids added to the N‐terminal of the canonical PTEN when CUG of the mRNA is u...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706501/ https://ncbi.nlm.nih.gov/pubmed/28631420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13236 |
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