Severe inhibition of lipooligosaccharide synthesis induces TLR2-dependent elimination of Mycobacterium marinum from THP1-derived macrophages

BACKGROUND: Although mycobacterial glycolipids are among the first-line molecules involved in host–pathogen interactions, their contribution in virulence remains incomplete. Mycobacterium marinum is a waterborne pathogen of fish and other ectotherms, closely related to Mycobacterium tuberculosis. Si...

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Udgivet i:Microb Cell Fact
Main Authors: Szulc-Kielbik, Izabela, Pawelczyk, Jakub, Kielbik, Michal, Kremer, Laurent, Dziadek, Jaroslaw, Klink, Magdalena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706390/
https://ncbi.nlm.nih.gov/pubmed/29183333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0829-z
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