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Structural basis of divergent cyclin‐dependent kinase activation by Spy1/RINGO proteins
Cyclin‐dependent kinases (Cdks) are principal drivers of cell division and are an important therapeutic target to inhibit aberrant proliferation. Cdk enzymatic activity is tightly controlled through cyclin interactions, posttranslational modifications, and binding of inhibitors such as the p27 tumor...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706343/ https://ncbi.nlm.nih.gov/pubmed/28666995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796905 |
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