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The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer
BACKGROUND: Spy1 is a novel 'cyclin-like' activator of the G1/S transition capable of enhancing cell proliferation as well as inhibiting apoptosis. Spy1 protein levels are tightly regulated during normal mammary development and forced overexpression in mammary mouse models accelerates mamm...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294245/ https://ncbi.nlm.nih.gov/pubmed/22280365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-45 |
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