The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer

BACKGROUND: Spy1 is a novel 'cyclin-like' activator of the G1/S transition capable of enhancing cell proliferation as well as inhibiting apoptosis. Spy1 protein levels are tightly regulated during normal mammary development and forced overexpression in mammary mouse models accelerates mamm...

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Détails bibliographiques
Auteurs principaux: Al Sorkhy, Mohammad, Ferraiuolo, Rosa-Maria, Jalili, Espanta, Malysa, Agnes, Fratiloiu, Andreea R, Sloane, Bonnie F, Porter, Lisa A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294245/
https://ncbi.nlm.nih.gov/pubmed/22280365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-45
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