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Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro
Families of cyclin-like proteins have emerged that bind and activate cyclin dependent kinases (Cdk)s, directing the phosphorylation of noncanonical Cdk substrates. One of these proteins, Spy1, has demonstrated the unique ability to directly bind and activate both Cdk1 and Cdk2, as well as binding an...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825785/ https://ncbi.nlm.nih.gov/pubmed/26771716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121327 |
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