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Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro
Families of cyclin-like proteins have emerged that bind and activate cyclin dependent kinases (Cdk)s, directing the phosphorylation of noncanonical Cdk substrates. One of these proteins, Spy1, has demonstrated the unique ability to directly bind and activate both Cdk1 and Cdk2, as well as binding an...
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| 出版年: | Cell Cycle |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825785/ https://ncbi.nlm.nih.gov/pubmed/26771716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121327 |
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