Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast

Sae2 promotes the repair of DNA double-strand breaks in Saccharomyces cerevisiae. The role of Sae2 is linked to the Mre11/Rad50/Xrs2 (MRX) complex, which is important for the processing of DNA ends into single-stranded substrates for homologous recombination. Sae2 has intrinsic endonuclease activity...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Arora, Sucheta, Deshpande, Rajashree A., Budd, Martin, Campbell, Judy, Revere, America, Zhang, Xiaoming, Schmidt, Kristina H., Paull, Tanya T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705816/
https://ncbi.nlm.nih.gov/pubmed/28970327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00156-17
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