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Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast
Sae2 promotes the repair of DNA double-strand breaks in Saccharomyces cerevisiae. The role of Sae2 is linked to the Mre11/Rad50/Xrs2 (MRX) complex, which is important for the processing of DNA ends into single-stranded substrates for homologous recombination. Sae2 has intrinsic endonuclease activity...
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| Publié dans: | Mol Cell Biol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705816/ https://ncbi.nlm.nih.gov/pubmed/28970327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00156-17 |
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