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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity
The microenvironment provides a functional substratum supporting tumour growth. Hyaluronan (HA) is a major component of this structure. While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in cancer are poorly understood. We show that the eukaryotic translation...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705209/ https://ncbi.nlm.nih.gov/pubmed/29111978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29830 |
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