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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity
The microenvironment provides a functional substratum supporting tumour growth. Hyaluronan (HA) is a major component of this structure. While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in cancer are poorly understood. We show that the eukaryotic translation...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705209/ https://ncbi.nlm.nih.gov/pubmed/29111978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29830 |
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