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Adding Polyamine Metabolism to the mTORC1 Toolkit in Cell Growth and Cancer

The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) is a major nutrient sensor and regulator of cellular metabolic flux. Reporting recently in Nature, Zabala-Letona et al. (2017) show that mTORC1 regulates an additional branch of metabolism in the cell—polyamine synthesis—that is import...

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Publicat a:Dev Cell
Autors principals: Gomes, Ana P., Schild, Tanya, Blenis, John
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705022/
https://ncbi.nlm.nih.gov/pubmed/28742999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.07.004
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