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Adding Polyamine Metabolism to the mTORC1 Toolkit in Cell Growth and Cancer
The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) is a major nutrient sensor and regulator of cellular metabolic flux. Reporting recently in Nature, Zabala-Letona et al. (2017) show that mTORC1 regulates an additional branch of metabolism in the cell—polyamine synthesis—that is import...
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| 發表在: | Dev Cell |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705022/ https://ncbi.nlm.nih.gov/pubmed/28742999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.07.004 |
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