Structure of an Hsp90 - Cdc37 - Cdk4 complex

Activation of many protein kinases depends on their interaction with the Hsp90 molecular chaperone system. Recruitment of protein kinase clients to the Hsp90 chaperone system is mediated by the co-chaperone adaptor protein Cdc37, which acts as a scaffold, simultaneously binding protein kinases and H...

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Publicat a:Mol Cell
Autors principals: Vaughan, Cara K., Göhlke, Ulrich, Sobott, Frank, Good, Valerie M., Ali, Maruf M. U., Prodromou, Chrisostomos, Robinson, Carol V., Saibil, Helen R., Pearl, Laurence H.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704897/
https://ncbi.nlm.nih.gov/pubmed/16949366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.07.016
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