Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells

ATP7B is a copper-transporting P(1B)-type ATPase (Cu-ATPase) with an essential role in human physiology. Mutations in ATP7B cause the potentially fatal Wilson disease, and changes in ATP7B expression are observed in several cancers. Despite its physiologic importance, the biochemical information abo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Jayakanthan, Samuel, Braiterman, Lelita T., Hasan, Nesrin M., Unger, Vinzenz M., Lutsenko, Svetlana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704462/
https://ncbi.nlm.nih.gov/pubmed/28842499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807263
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