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Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells
ATP7B is a copper-transporting P(1B)-type ATPase (Cu-ATPase) with an essential role in human physiology. Mutations in ATP7B cause the potentially fatal Wilson disease, and changes in ATP7B expression are observed in several cancers. Despite its physiologic importance, the biochemical information abo...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704462/ https://ncbi.nlm.nih.gov/pubmed/28842499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807263 |
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