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Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells
ATP7B is a copper-transporting P(1B)-type ATPase (Cu-ATPase) with an essential role in human physiology. Mutations in ATP7B cause the potentially fatal Wilson disease, and changes in ATP7B expression are observed in several cancers. Despite its physiologic importance, the biochemical information abo...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704462/ https://ncbi.nlm.nih.gov/pubmed/28842499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807263 |
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