Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

Telomerase-specific replication-competent adenoviruses (Ads), i.e., TRADs, which possess an E1 gene expression cassette driven by the human telomerase reverse transcriptase promoter, are promising agents for cancer treatment. However, even though oncolytic Ads, including TRAD, are intratumorally adm...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Oncolytics
Hoofdauteurs: Machitani, Mitsuhiro, Sakurai, Fuminori, Wakabayashi, Keisaku, Nakatani, Kosuke, Tachibana, Masashi, Kato, Nobuyuki, Fujiwara, Toshiyoshi, Mizuguchi, Hiroyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704103/
https://ncbi.nlm.nih.gov/pubmed/29202008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.10.003
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