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Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

Telomerase-specific replication-competent adenoviruses (Ads), i.e., TRADs, which possess an E1 gene expression cassette driven by the human telomerase reverse transcriptase promoter, are promising agents for cancer treatment. However, even though oncolytic Ads, including TRAD, are intratumorally adm...

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Podrobná bibliografie
Vydáno v:Mol Ther Oncolytics
Hlavní autoři: Machitani, Mitsuhiro, Sakurai, Fuminori, Wakabayashi, Keisaku, Nakatani, Kosuke, Tachibana, Masashi, Kato, Nobuyuki, Fujiwara, Toshiyoshi, Mizuguchi, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704103/
https://ncbi.nlm.nih.gov/pubmed/29202008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.10.003
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