Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

Telomerase-specific replication-competent adenoviruses (Ads), i.e., TRADs, which possess an E1 gene expression cassette driven by the human telomerase reverse transcriptase promoter, are promising agents for cancer treatment. However, even though oncolytic Ads, including TRAD, are intratumorally adm...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Machitani, Mitsuhiro, Sakurai, Fuminori, Wakabayashi, Keisaku, Nakatani, Kosuke, Tachibana, Masashi, Kato, Nobuyuki, Fujiwara, Toshiyoshi, Mizuguchi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704103/
https://ncbi.nlm.nih.gov/pubmed/29202008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.10.003
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