Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

Telomerase-specific replication-competent adenoviruses (Ads), i.e., TRADs, which possess an E1 gene expression cassette driven by the human telomerase reverse transcriptase promoter, are promising agents for cancer treatment. However, even though oncolytic Ads, including TRAD, are intratumorally adm...

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Bibliografske podrobnosti
izdano v:Mol Ther Oncolytics
Main Authors: Machitani, Mitsuhiro, Sakurai, Fuminori, Wakabayashi, Keisaku, Nakatani, Kosuke, Tachibana, Masashi, Kato, Nobuyuki, Fujiwara, Toshiyoshi, Mizuguchi, Hiroyuki
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704103/
https://ncbi.nlm.nih.gov/pubmed/29202008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.10.003
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