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Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus

After mitosis, nuclear reorganization occurs together with decondensation of mitotic chromosomes and reformation of the nuclear envelope, thereby restoring the Ran-GTP gradient between the nucleus and cytoplasm. The Ran-GTP gradient is dependent on Pim1/RCC1. Interestingly, a defect in Pim1/RCC1 in...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Aoki, Keita, Niki, Hironori
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703609/
https://ncbi.nlm.nih.gov/pubmed/28954740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.027193
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