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Predictive model identifies key network regulators of cardiomyocyte mechano-signaling
Mechanical strain is a potent stimulus for growth and remodeling in cells. Although many pathways have been implicated in stretch-induced remodeling, the control structures by which signals from distinct mechano-sensors are integrated to modulate hypertrophy and gene expression in cardiomyocytes rem...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703578/ https://ncbi.nlm.nih.gov/pubmed/29131824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005854 |
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