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High content analysis identifies unique morphological features of reprogrammed cardiomyocytes

Direct reprogramming of fibroblasts into cardiomyocytes is a promising approach for cardiac regeneration but still faces challenges in efficiently generating mature cardiomyocytes. Systematic optimization of reprogramming protocols requires scalable, objective methods to assess cellular phenotype be...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sutcliffe, Matthew D., Tan, Philip M., Fernandez-Perez, Antonio, Nam, Young-Jae, Munshi, Nikhil V., Saucerman, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775342/
https://ncbi.nlm.nih.gov/pubmed/29352247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19539-z
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