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Computational Model of Cardiomyocyte Apoptosis Identifies Mechanisms of Tyrosine Kinase Inhibitor-Induced Cardiotoxicity

Despite clinical observations of cardiotoxicity among cancer patients treated with tyrosine kinase inhibitors (TKIs), the molecular mechanisms by which these drugs affect the heart remain largely unknown. Mechanistic understanding of TKI-induced cardiotoxicity has been limited in part due to the com...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Cardiol
Egile Nagusiak: Grabowska, Monika E., Chun, Bryan, Moya, Raquel, Saucerman, Jeffrey J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154673/
https://ncbi.nlm.nih.gov/pubmed/33667419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.02.014
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