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Cell-to-cell variation sets a tissue-rheology–dependent bound on collective gradient sensing
When a single cell senses a chemical gradient and chemotaxes, stochastic receptor–ligand binding can be a fundamental limit to the cell’s accuracy. For clusters of cells responding to gradients, however, there is a critical difference: Even genetically identical cells have differing responses to che...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703308/ https://ncbi.nlm.nih.gov/pubmed/29114053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712309114 |
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