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Cell-to-cell variation sets a tissue-rheology–dependent bound on collective gradient sensing

When a single cell senses a chemical gradient and chemotaxes, stochastic receptor–ligand binding can be a fundamental limit to the cell’s accuracy. For clusters of cells responding to gradients, however, there is a critical difference: Even genetically identical cells have differing responses to che...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Camley, Brian A., Rappel, Wouter-Jan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703308/
https://ncbi.nlm.nih.gov/pubmed/29114053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712309114
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