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A protein interaction mechanism for suppressing the mechanosensitive Piezo channels

Piezo proteins are bona fide mammalian mechanotransduction channels for various cell types including endothelial cells. The mouse Piezo1 of 2547 residues forms a three-bladed, propeller-like homo-trimer comprising a central pore-module and three propeller-structures that might serve as mechanotransd...

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Publicado en:Nat Commun
Autores principales: Zhang, Tingxin, Chi, Shaopeng, Jiang, Fan, Zhao, Qiancheng, Xiao, Bailong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702604/
https://ncbi.nlm.nih.gov/pubmed/29176668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01712-z
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