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A protein interaction mechanism for suppressing the mechanosensitive Piezo channels

Piezo proteins are bona fide mammalian mechanotransduction channels for various cell types including endothelial cells. The mouse Piezo1 of 2547 residues forms a three-bladed, propeller-like homo-trimer comprising a central pore-module and three propeller-structures that might serve as mechanotransd...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Tingxin, Chi, Shaopeng, Jiang, Fan, Zhao, Qiancheng, Xiao, Bailong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702604/
https://ncbi.nlm.nih.gov/pubmed/29176668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01712-z
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