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The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction
The beating heart possesses the intrinsic ability to adapt cardiac output to changes in mechanical load. The century-old Frank–Starling law and Anrep effect have documented that stretching the heart during diastolic filling increases its contractile force. However, the molecular mechanotransduction...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7870949/ https://ncbi.nlm.nih.gov/pubmed/33558521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21178-4 |
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