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Combining engineered nucleases with adeno-associated viral vectors for therapeutic gene editing
With the recent advent of several generations of targeted DNA nucleases, most recently CRISPR/Cas9, genome editing has become broadly accessible across the biomedical community. Importantly, the capacity of these nucleases to modify specific genomic loci associated with human disease could render ne...
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| 發表在: | Adv Exp Med Biol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702533/ https://ncbi.nlm.nih.gov/pubmed/29130152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-63904-8_2 |
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