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Engineering adeno-associated viruses for clinical gene therapy

Clinical gene therapy has been increasingly successful, due both to an enhanced molecular understanding of human disease and to progressively improving gene delivery technologies. Among the latter, delivery vectors based on adeno-associated virus (AAV) have emerged as safe and effective – in one rec...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Kotterman, Melissa A., Schaffer, David V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393649/
https://ncbi.nlm.nih.gov/pubmed/24840552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3742
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