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Combining engineered nucleases with adeno-associated viral vectors for therapeutic gene editing

With the recent advent of several generations of targeted DNA nucleases, most recently CRISPR/Cas9, genome editing has become broadly accessible across the biomedical community. Importantly, the capacity of these nucleases to modify specific genomic loci associated with human disease could render ne...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Epstein, Benjamin E., Schaffer, David V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702533/
https://ncbi.nlm.nih.gov/pubmed/29130152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-63904-8_2
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