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Prospective diagnosis of sporadic CJD by the detection of abnormal PrP in patient urine
IMPORTANCE: CJD is a fatal neurodegenerative disorder associated with the accumulation of infectious abnormal PrP through a mechanism of templated misfolding. A recent report has described the detection of abnormal PrP in vCJD patient urine using protein misfolding by cylic amplification, which was...
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| Publicado no: | JAMA Neurol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701732/ https://ncbi.nlm.nih.gov/pubmed/27699415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.3733 |
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