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Diffusion-weighted MRI signal abnormality in sporadic CJD increases in extent and intensity with disease duration

IMPORTANCE: Prion diseases represent the archetype of brain diseases caused by protein misfolding, the commonest subtype being sporadic Creutzfeldt-Jakob disease (sCJD), a rapidly progressive dementia. Diffusion weighted iimaging (DWI) has emerged as the most sensitive MRI sequence for the diagnosis...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Eisenmenger, Laura, Porter, Marie-Claire, Carswell, Christopher, Thompson, Andrew, Mead, Simon, Rudge, Peter, Collinge, John, Jäger, Rolf, Hyare, Harpreet
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837002/
https://ncbi.nlm.nih.gov/pubmed/26569479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.3159
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