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Transcriptional circuits in B cell transformation

Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to glucocorticoid-mediated cell death. B cell acute lymphoblastic leukemias originating from...

詳細記述

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書誌詳細
出版年:Curr Opin Hematol
主要な著者: Hu, Yeguang, Yoshida, Toshimi, Georgopoulos, Katia
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701664/
https://ncbi.nlm.nih.gov/pubmed/28463873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000352
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