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Transcriptional circuits in B cell transformation
Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to glucocorticoid-mediated cell death. B cell acute lymphoblastic leukemias originating from...
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| Publicado no: | Curr Opin Hematol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701664/ https://ncbi.nlm.nih.gov/pubmed/28463873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000352 |
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