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Transcriptional circuits in B cell transformation

Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to glucocorticoid-mediated cell death. B cell acute lymphoblastic leukemias originating from...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Opin Hematol
Egile Nagusiak: Hu, Yeguang, Yoshida, Toshimi, Georgopoulos, Katia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701664/
https://ncbi.nlm.nih.gov/pubmed/28463873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000352
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