Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in Hematopoietic Stem Cells

Here we investigate the mechanisms that underlie the induction of developmental potential and establishment of cell fate during early hematopoiesis. A cascade of lineage-affiliated gene expression signatures, primed in hematopoietic stem cells (HSC) and differentially propagated in lineage-restricte...

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Main Authors: Ng, Samuel Yao-Ming, Yoshida, Toshimi, Zhang, Jiangwen, Georgopoulos, Katia
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012962/
https://ncbi.nlm.nih.gov/pubmed/19345118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.01.014
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