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High-Throughput Approaches to Pinpoint Function within the Noncoding Genome

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas nuclease system is a powerful tool for genome editing, and its simple programmability has enabled high-throughput genetic and epigenetic studies. These high-throughput approaches offer investigators a toolkit for functional i...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Montalbano, Antonino, Canver, Matthew C., Sanjana, Neville E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701515/
https://ncbi.nlm.nih.gov/pubmed/28985510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.017
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