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CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing
MOTIVATION: Clustered regularly interspaced short palindromic repeats (CRISPR) technologies allow for facile genomic modification in a site-specific manner. A key step in this process is the in silico design of single guide RNAs to efficiently and specifically target a site of interest. To this end,...
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| Pubblicato in: | Bioinformatics |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141852/ https://ncbi.nlm.nih.gov/pubmed/31764961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz867 |
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