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Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments
CRISPR (clustered regularly interspaced short palindromic repeats) genome-editing experiments offer enormous potential for the evaluation of genomic loci using arrayed single guide RNARNARNAs (sgRNAs) or pooled sgRNA libraries. Numerous computational tools are available to help design sgRNAs with op...
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| Publicado no: | Nat Protoc |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182299/ https://ncbi.nlm.nih.gov/pubmed/29651054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2018.005 |
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