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CRISPR screens to discover functional noncoding elements
A major challenge in genomics is to identify functional elements in the noncoding genome. Recently, pooled CRISPR mutagenesis screens of noncoding regions have emerged as a novel method for finding elements that impact gene expression and phenotype-/disease-relevant biological processes. Here we rev...
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| Publicado no: | Trends Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992445/ https://ncbi.nlm.nih.gov/pubmed/27423542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2016.06.004 |
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